If you are using the latest version of Yii (1.1.11), then you have a few new options in CBreadcrumbs, namely: activeLinkTemplate and inactiveLinkTemplate and using these (and also tagName) you can easily achieve your requirement.
You just need to add values for these options, in the file where you are including the breadcrumb widget, by default, it’s in a layout file : protected/views/layouts/main.php , like this:
<?php if(isset($this->breadcrumbs)):?>
<?php $this->widget('zii.widgets.CBreadcrumbs', array(
'links'=>$this->breadcrumbs,
'tagName'=>'ul', // will change the container to ul
'activeLinkTemplate'=>'<li><a href="{url}">{label}</a></li>', // will generate the clickable breadcrumb links
'inactiveLinkTemplate'=>'<li>{label}</li>', // will generate the current page url : <li>News</li>
'homeLink'=>'<li><a href="'.Yii::app()->homeUrl.'">Home</a></li>' // will generate your homeurl item : <li><a href="/dr/dr/public_html/">Home</a></li>
)); ?><!-- breadcrumbs -->
'links'=>$this->breadcrumbs,
'tagName'=>'ul', // will change the container to ul
'htmlOptions'=>array('class'=>'menu'),
// ... rest of the code ...
It was a great help for me, cause I tried to turn a HTML5 code snippet into the Yii CBreadcrumb Widget code form. I couldn’t find anything useful until I found these posts.